Mine took about a week, I've been taking 600 mg three times a day for over three years now, considering when I first started to where I am now yes it helps tremendously, but I'm still into much severe pain to be able really function. Good luck my lady

It took mine a couple of days and it still does not make me sleepy, wish it did at night. Hope you have great relief with it.

I could tell a difference within a few days. I take one in the morning along with Lexapro, and 2 Gabapentins each night before bed along with a muscle relaxer to help me sleep. It really helps ease the restless leg problems too!

@A MyFibroTeam Member I loved Savella so much. But, it had a side effect I couldn't live with. It made me extremely grumpy. But, it helped my pain tremendously! And it worked fast. I really hope you get approved & that it works great for you!

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