Overview
Savella is a prescription medication approved by the Food and Drug Administration (FDA) in 2009 for the treatment of fibromyalgia. The drug name of Savella is Milnacipran. Savella is not a cure for fibromyalgia, but it can reduce pain and improve well-being for some people with fibromyalgia.

Savella must be used with caution and closely monitored in people with a history of depression, liver or kidney problems, dysyria (pain or difficulty during urinating), high or low blood pressure, diabetes, seizures, or alcohol dependence. Savella is not suitable for use by women who are pregnant or breastfeeding.
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Savella is in the serotonin-norepinephrine reuptake inhibitor (SNRI) class of drugs, which includes many antidepressants. It is believed that Savella works in cases of fibromyalgia by blocking pain signals sent by nerves.

How do I take it?
Savella is a tablet taken orally twice a day. Savella may be taken with or without food. Taking Savella with food may help prevent some side effects. It is important to take Savella at approximately the same times each day. Ask your doctor about drinking alcohol while taking Savella.

Certain common analgesic drugs (painkillers) such as aspirin, ibuprofen, and naproxen may exacerbate some side effects. Avoid taking these drugs while taking Savella.

If you decide to stop taking Savella, consult your doctor on how to taper off. Do not abruptly stop taking Savella.

Always follow your doctor’s instructions exactly when taking Savella.

Results
In a study completed in 2006, 1,196 people with fibromyalgia were given Milnacipran (Savella). A significant number of participants experienced more than a 30 percent improvement in pain, and many also reported significant improvements in overall well-being.

Side effects
Common side effects of Savella include headache, nausea, constipation, diarrhea, sweating, and hot, flushed skin.

Call your doctor if you experience stomach pain, confusion, changes in amount or color of urine, muscle tremors, changes in heartbeat, hallucination, agitation, easy bruising, unusual bleeding, or yellowing of your eyes or skin while taking Savella.

Some people experience neurological symptoms including depression or suicidal thoughts while taking Savella. Contact your doctor if you experience these side effects.

Savella can also cause allergic or hypersensitive reactions. Get medical help immediately if you experience difficulty breathing or swelling in the face, throat, eyes, lips, or tongue.

Savella (Milnacipran) Questions

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