Savella is a prescription medication approved by the Food and Drug Administration (FDA) in 2009 for the treatment of fibromyalgia. The drug name of Savella is Milnacipran. Savella is not a cure for fibromyalgia, but it can reduce pain and improve well-being for some people with fibromyalgia.
Savella must be used with caution and closely monitored in people with a history of depression, liver or kidney problems, dysyria (pain or difficulty during urinating), high or low blood pressure, diabetes, seizures, or alcohol dependence. Savella is not suitable for use by women who are pregnant or breastfeeding.
Savella is in the serotonin-norepinephrine reuptake inhibitor (SNRI) class of drugs, which includes many antidepressants. It is believed that Savella works in cases of fibromyalgia by blocking pain signals sent by nerves.
How do I take it?
Savella is a tablet taken orally twice a day. Savella may be taken with or without food. Taking Savella with food may help prevent some side effects. It is important to take Savella at approximately the same times each day. Ask your doctor about drinking alcohol while taking Savella.
Certain common analgesic drugs (painkillers) such as aspirin, ibuprofen, and naproxen may exacerbate some side effects. Avoid taking these drugs while taking Savella.
If you decide to stop taking Savella, consult your doctor on how to taper off. Do not abruptly stop taking Savella.
Always follow your doctor’s instructions exactly when taking Savella.
In a study completed in 2006, 1,196 people with fibromyalgia were given Milnacipran (Savella). A significant number of participants experienced more than a 30 percent improvement in pain, and many also reported significant improvements in overall well-being.
Common side effects of Savella include headache, nausea, constipation, diarrhea, sweating, and hot, flushed skin.
Call your doctor if you experience stomach pain, confusion, changes in amount or color of urine, muscle tremors, changes in heartbeat, hallucination, agitation, easy bruising, unusual bleeding, or yellowing of your eyes or skin while taking Savella.
Some people experience neurological symptoms including depression or suicidal thoughts while taking Savella. Contact your doctor if you experience these side effects.
Savella can also cause allergic or hypersensitive reactions. Get medical help immediately if you experience difficulty breathing or swelling in the face, throat, eyes, lips, or tongue.
Learn more about living with fibromyalgia and treatment with Savella. Free tips, tools and facts to help you and your doctor decide if Savella is right for you. Click here to learn more.
Learn more about living with fibromyalgia and treatment with Savella. Free tips, tools and facts to help you and your doctor decide if Savella is right for you. Click here to learn more.show less
SAVELLA may be associated with serious side effects. Call your healthcare provider right away or seek emergency help if you experience any of the following symptoms:
Do not stop SAVELLA without first talking to your healthcare provider. Stopping SAVELLA too quickly may cause serious symptoms, including:
SAVELLA is not for everyone. Do not take SAVELLA if you:
Before starting SAVELLA, tell your healthcare provider:
Other Safety Information related to SAVELLA:
Most common side effects of SAVELLA:
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/Safety/Medwatch, or call 1-800-FDA-1088.
The information provided in this site is intended for US residents only. The products described on this site may have different product labeling in countries outside of the United States.show less
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