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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyFibroTeam Member asked a question 💭
Cortland, NY
5 days ago
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A MyFibroTeam Member

@A MyFibroTeam Member I know last night was so difficult. I'm just checking in on you. How are you holding up today?
I understand that living with severe me/cfs is more difficult than most of us can even imagine, but we try. We care about you and we wish we could help! Let us know how you're doing, friend, if you have the energy/when you are able, ok?

5 days ago
A MyFibroTeam Member

Hi Trevor, I think it might be because the mitochondria is disabled.
The mitochondria is part of our cells that makes ✨energy✨.
It is possible that inflammation created damage in the mitochondria.
The inflammation might have been due to a virus, for example, for some people.
Scientists are still trying to figure it out but this is one theory.

https://www.youtube.com/watch?v=l1ufdoV5vYY

https://pmc.ncbi.nlm.nih.gov/articles/PMC12151296/

Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
5 days ago
A MyFibroTeam Member

Thank you for the added information, it is very helpful to me to be reminded how my fibro/CFS started. I figured I must have had it when I was a teenager because I had really heavy periods all the time, at least until I finally had menopause, I just didn't know what it was (this was back in the late 60s to around 60, but then I had other issues.

Hope you all are doing as well as can be expected.

5 days ago
MyFibroTeam

Since you're managing fibromyalgia, it's worth focusing on the fatigue that comes with it, as the two experiences can feel very similar and are often talked about together in the fibromyalgia community.

Fibromyalgia-related fatigue has several known contributors:

- Brain changes – The part of the brain that processes Show Full Answer

Since you're managing fibromyalgia, it's worth focusing on the fatigue that comes with it, as the two experiences can feel very similar and are often talked about together in the fibromyalgia community.

Fibromyalgia-related fatigue has several known contributors:

- Brain changes – The part of the brain that processes sensory information (the thalamus) may become overloaded by constant pain signals, leading to less gray matter and more fatigue
- Poor sleep – Many people with fibromyalgia don't reach deep, restorative sleep, leaving them exhausted even after a full night's rest
- Muscle inefficiency – Muscles in fibromyalgia require more energy than usual and don't always relax properly between use
- Melatonin disruption – Fibromyalgia can interfere with the body's natural sleep-wake chemical, making you feel sleepy at the wrong times
- Immune system activity – Increased immune cell activation in the central nervous system is also linked to fatigue

One MyFibroTeam member described it as feeling "like an old, damp, worn-out cloth, with no energy and no strength."

If your fatigue feels new or worse than usual, it's a good idea to check in with your care team to rule out other contributing factors.

5 days ago

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A MyFibroTeam Member asked a question 💭
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A MyFibroTeam Member asked a question 💭
Cortland, NY