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“Amatica exists for one reason: to move ME/CFS, Long COVID and chronic disease care away from guesswork by learning from large-scale, real-world patient data, and ultimately to match patients to effective treatments and improve care for the entire patient population.
2025 at a glance
In 2025, Amatica Health:
Launched publicly in January 2025
Grew to nearly 300 unique patients contributing health history, questionnaires, and blood samples
Rolled out two core testing modalities:
A 31-marker… read more
Great question!
My own limited experience and understanding is: there are specialty clinics such as the one in Florida, US, where a doctor who focuses on ME/CFS (Dr. Nancy Klimas) can test for highly specific things.
However, I think most long covid clinics and in general, doctors helping patients with LC or ME/CFS will routinely order labs to rule out anything else that might be going on and focus on what's considered best practices in terms of what's prescribed (as in Stanford).
Unfortunately I've heard of some well known clinics still pushing G.E.T. and CBT for people who literally are diagnosed with ME/CFS, i.e. they experience PEM. 💔
The 2026 International ME/CFS Conference took place on May 7–8, 2026, in Berlin:
https://events.mecfs-research.org/en/events/con...
The history of diagnosing and treating ME/CFS is like a combination mystery novel and horror movie. It's amazingly detailed in a book I want to recommend highly:
Through the Shadowlands: A Science Writer's Odyssey into an Illness Science Doesn't... by Julie Rehmeyer
https://pbs.twimg.com/media/HHt62ksW0Acy1By?for...
2026 ME/CFSConference
2026 ME/CFS 2026 Conference
May 7-8 2026
amaticahealth.com also discusses 3 topics on their site.
1) Reduced BH1/BH2 ratio in LC and ME/CFS.
A metabolic window in vascular and neurological disfunction.
2)HIF1a elevation correlated with mitochondrial, fibrotic, and immunosuppressive protein in a subset of ME/CFS and LC patients.
3) TGFB2 elevated in subgroup of ME/CFS andLC patients. Correlation with hypoxia and mitochondrial recycling related protein.
( I posted this Q and A because so many with fibromyalgia have ME/CFS.)
* Site mentioned that if one was in a POTS flare, that could be noticed in the blood draw…..
Pop on Google. All the information you need is there about all the questions you asked 🌻✨️🌼
That's a really interesting question! While Amatica Health's research is focused on conditions that aren't fibromyalgia, there's a reason this might still feel relevant to you.
Fibromyalgia is notoriously difficult to diagnose because there's no single definitive test for it. Doctors currently diagnose it by:
- Ruling out Show Full Answer
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