I have found that oral antihistamines do nothing for itching. Years ago I used lanacane. I found that was the best thing for itching. I don't know if it's still on the market or not have not been in a drugstore in a while. Maybe you could ask your pharmacist. It's an over-the-counter product. Also you can try Benadryl cream. I find that helps with rashes. Works better than the oral Benadryl.

My dosage is every six hours....wonder what the difference is?

I have only one area, a small patch on my left waistband area that itches frequently. The skin has now got a goosebump like texture in that area.

I'm on the same med and today i had to take 2, and 3 benadryls for the swelling of my lips and tongue.. My itching gets bad when something I'm allergic to is in the air and my allergies are bad. That's when i get itchy. Or when i take a opiate, touch strawberry leaves. Certain plants make me itch. Detergents. I've been through the ringer w my doctor's, specialist's, having me write it down.

I am constantly itchy. It’s not at a terrorizing level, and I’ve learned to ignore most of it most of the time. But OMGoodness if I can get the Hubster to “scratch” my back with my dry brush..: heaven.