Hi! I’m currently on Lyrica but it has started to not work as it did before. My pain level has been very high lately so my doctor prescribed me Effexor (venlafaxine) but I haven’t taken it yet. A friend of mine said it changed her life and she feels better than she has in a long time. She’s not a fibromyalgia suffer, but has chronic fatigue syndrome. I’ve been hesitant to try it because of the side effects but I am because I’m desperate. I will update you when I do.

Call your doctor who prescribed them if you are concerned. Don't take anymore until you speak with the doctor.

I take it (currently a total of 112.5mg, spread across two tablets in the morning and one in the evening) and feel like it does help with my fibromyalgia but agree that it can take a little while for your body to adjust to it, especially when first taking it and/or increasing your dosage (my main side effect has been nausea but gastro resistant tablets help). Also agree that if you miss/delay taking a dose that you know about it. For the most part though, it does help to take the edge off.

I took Venlafaxine for years for depression. Helped with this not Fibromyalgia. If you miss a dose you know it. I took six months to gradually come off it no problems.

Hi! I wish I could help you, but this class of medication has serious side effects for me. It is a personal preference, but I know that if like when I took a medication for 3 days it took 3 days to wear off and it was severe side effects, but they tried to tell me it would get better. I knew it was getting worse so I just stopped as I was afraid as other medications did me awful. I always say we all have a lot in common but no two of us are the same. Hugs and prayers. God bless.