I wear a 44 DDD, and lane byrant has a bra that has no underwire, crisscross in back with no clasp. It is great doesn't hold them as high as wire, but holds them well. And they dont hurt

I am surprised that no one mentioned UNIQLO's wireless bras.

https://www.youtube.com/watch?v=uj34iGkBeQc

https://www.uniqlo.com/us/en/page/intimates-fea...

I can't wear any other bras now. UNIQLO's seamless shorts are also really comfortable as if you're not wearing anything. Highly recommended!

I have bamboo band liners for all my bras they pad so they don't hurt and they absorb sweat to keep it off your skin

I don't wear a bra at home and if I'm just going to be running to the grocery store or drug store, I don't. But anywhere else I do. And, its the first thing I take off when I get home. It was recommended that I wear one with wire because I'm a 36D but I gave that up quite a while ago, I have to be comfortable.

Quite a while back someone asked this very question and someone responded that the soft bras that you can purchase online after having a masectomy are very soft for fibro. I never looked into it but maybe that'll help.