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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyFibroTeam Member asked a question 💭
Addlestone, UK

So as many of you will relate to. I have trouble sleeping; whether that be due to leg spasms, pain or general inability to switch off. A friend of my cousin who has fibro recommended amytriptyline. Can anyone give me some insight if they have used it? Or other recommendations to help get some sleep?

Also if anyone else has random leg spasms, how do you deal with it/make it stop? I've had them last an entire night before on and off and I have no idea what to do about it

October 3, 2018
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Answer Summary

Members shared varied experiences with amytriptyline for fibromyalgia-related sleep issues and leg spasms, with some finding success at lower... Read more

Members shared varied experiences with amytriptyline for fibromyalgia-related sleep issues and leg spasms, with some finding success at lower doses (10-12.5mg) while others reported side effects including emotional changes, zombie-like feelings, and weight gain that led them to switch medications. Several members recommended alternatives that worked better for them, including nortriptyline (with fewer side effects), melatonin combined with low-dose medication, ropinirole or Klonopin specifically for restless legs, and mirtazapine for reliable sleep onset. A recurring theme was that everyone metabolizes medications differently, so members encouraged starting low, working closely with a doctor to find the right fit, and not being afraid to try alternatives until finding what works best for your individual body.

A MyFibroTeam Member

Melatonin is pretty good.

October 3, 2018
A MyFibroTeam Member

Ropinirole (brand name requip) helps my husband immensely with his restless leg syndrome.

October 3, 2018
A MyFibroTeam Member

I'm on amytriptyline and it definitely has helped me to sleep better.

October 3, 2018
A MyFibroTeam Member

I've been on trepilene for 15 years and my dosage now is 125 mg. The doctor explained that it makes you sleep. It is also an anti-depressant and pain killer. I attribute my weight gain on this medication even though the Rheumatologist denies it. I grew from size 34 to 44 size.

October 3, 2018
A MyFibroTeam Member

I have used it also. I ended up on to much of it and had bad side effects. I just switched to nortriptyline and no side effects at all. They are both Tryciclic antidepressants and older meds and help stay asleep. Good luck!

October 3, 2018

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