I was having horrible calf and shin area cramping. It would keep me up at night. I was tested aggressively for MS.The dr officially diagnosed me with "chronic severe fibro" but no MS .What he did find was that I had a bad B-12 deficiency so I have been taking it plus Vit D and magnesium for over a year. My leg cramps stopped the second day of taking the B12.

I am sorry for your pain. As a thought, are you good at pacing yourself? Nutrition? Gentle exercise? You probably know the drill. Those are other big things that I am still learning to do that helps my pain levels a little. There are a Lot of wonderful natural suggestions on here. Keep reading and asking. Sometimes there just isn't another answer and meds may have to be the answer for awhile. I hope you find something soon that works for you hon

If you needed a blood transfusion then your body is not absorbing iron & B12 correctly. I am a nurse & since you needed a blood transfusion your doctor is legally responsible for finding out why & that means all testing for all vitamin deficientcies.

I take vitamin d everyday and about every 3 months a prescribed amount of D . My DR say's I do not absorb the D or the b12 so I will always need supplements and be checked often.

Jantannerfears....I take 1000mcg of B12 and 250 to 500 MG of magnesium. I also take 1000mg of D3