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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyFibroTeam Member asked a question 💭
Rensselaer, IN

Anyone tried or is taking Amitriptyline? Pros/Cons. Was thinking about trying it, if so what is a good starting dose to avoid side effects.

August 21, 2015
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Answer Summary

Members shared mixed experiences with amitriptyline for fibromyalgia, with many reporting that while it effectively reduced burning pain and... Read more

Members shared mixed experiences with amitriptyline for fibromyalgia, with many reporting that while it effectively reduced burning pain and helped with sleep, it came with challenging side effects including significant weight gain, brain fog, fatigue, and acne that lingered even after stopping the medication. Several members described feeling like zombies or unable to function during the day, though a few found relief at lower doses of 10mg to 50mg without major hangover effects. A recurring theme was that medications affect everyone differently, and while some members recommended trying it under medical supervision with the option to stop if side effects become too burdensome, the overall consensus leaned toward more cons than pros for this particular medication.

A MyFibroTeam Member

Jmalone75...if you et your MD want to try it it doesn't hurt just to try. Need to remember medications work diff. on everyone. If doesn't work or side effects get to you then your MD can wean you off et try you on something else. I've been a guinea pig for the last 15+ yr between migraine medications et now fibro et I have gone thru a lot of them for migraines that never worked from BP meds, to seizure medications, et cannot tell you how many migraine meds alone to take them away et they do not work on me:( My pt. what can it hurt?

August 23, 2015
A MyFibroTeam Member

Each person is different but from reading other comments it seems it has more cons than pros.

My doctor started me on 10mg, I didn't get any pain relief but it helped me fall asleep for a few hours for the first week or two.

I then gained 20lbs within 2 & a half months, got quite bad acne which I have never suffered from in my life.

I was taken off it back in April & still struggling to lose the weight & clear the acne.

Horrid medication for me personally.

August 23, 2015
A MyFibroTeam Member

I found it helped me to sleep and dulled my pain which made me feel more like a normal person. Didn't notice any of the side effects as fibro already caused most of them x

August 25, 2015
A MyFibroTeam Member

My doctor started me on it a few weeks ago and wants me to titrate up every few days. I started at 10mg and am currently at 50mg. No hangover feeling at all, and sleep is very slightly improved....

August 22, 2015
A MyFibroTeam Member

I have been on 50mg of this for 8 years now they did help me at first but the side effects don't seem worth it but I'm used to them they will be different for each person x

August 22, 2015

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