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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

My Doctor said to me if you stop the medicine for a few days you can know if it works. So I did and it was horrible. I also found out that Diluxetene/Cymbalta is not a medicine you don't want to stop for even 1 dose. The side affects had me all over the place. My pressure up higher pain ungodly buzzing in the ear couldn't focus with dizziness and nausea. So how do I know if the medicine works or if it's the side affects of coming off the medicine. Because now I feel like something else could be… read more

February 9
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A MyFibroTeam Member

You need to tapper off the Cymbalta and note severity of symptoms everyday in a journal while you are doing it. This will give you an accurate record of how your body reacts to the gradual withdrawal of the Cymbalta.

February 9
A MyFibroTeam Member

I went to a neurologist when I started having severe dizziness causing me to fall frequently and some other weird neuro symptoms. the doctor run alot of tests and finally did a panel of genetic test and found I have cerebellar ataxia. If you feel that it's something else than your fibro, get it checked out. You know your body more than anyone else.

February 10
MyFibroTeam

How do you know if your fibromyalgia medication is working, especially after experiencing severe withdrawal symptoms from stopping Cymbalta?

What you experienced when stopping Cymbalta (duloxetine) was likely withdrawal, not a sign the medication wasn't working. Cymbalta is an SNRI antidepressant that shouldn't be stopped Show Full Answer

How do you know if your fibromyalgia medication is working, especially after experiencing severe withdrawal symptoms from stopping Cymbalta?

What you experienced when stopping Cymbalta (duloxetine) was likely withdrawal, not a sign the medication wasn't working. Cymbalta is an SNRI antidepressant that shouldn't be stopped suddenly - it needs to be tapered gradually under medical supervision to avoid exactly what you described: increased pain, dizziness, nausea, ear buzzing, and blood pressure changes.

The fact that stopping it was "horrible" actually suggests the medication *was* providing some benefit. When you suddenly remove it, your body reacts strongly because it had adjusted to having it.

Here's how to tell if your medication is actually working:

- Compare your symptoms now (while taking it regularly) to before you started it
- Track your pain levels, fatigue, and daily functioning over weeks, not days
- Notice if you can do more activities or sleep better than before treatment
- Keep a symptom journal to identify patterns

A MyFibroTeam member shared a similar experience: they stopped Cymbalta and switched to Prozac, which caused their pain to return and made them feel worse. When they went back on Cymbalta at a higher dose, things improved. About your concerns regarding other conditions:

It's understandable to question your diagnosis when you're still experiencing pain, but fibromyalgia medications rarely eliminate all symptoms completely. They typically reduce severity and improve quality of life rather than providing complete relief.

If you have new or different symptoms that don't fit your fibromyalgia pattern, discussing them with a neurologist is reasonable. However, it's important to work with your current doctor first about:

- Whether your Cymbalta dose is optimal (it can be adjusted)
- Adding other fibromyalgia treatments alongside it
- Trying different medication combinations
- Incorporating non-drug approaches like physical therapy or cognitive behavioral therapy

Important: Never stop Cymbalta or similar medications abruptly again. If you and your doctor decide to try something different, you'll need a gradual tapering schedule to avoid withdrawal symptoms.

Many people with fibromyalgia need multiple approaches - medication plus lifestyle changes - to manage symptoms effectively. The goal is improvement, not perfection.

February 9
A MyFibroTeam Member

Thanks appreciate you 🙏

February 9

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