I take lyrica 150mg. It takes away the restless leg issue for me. My not help everyone but from my experience it helped tremendously.

I am not sure because I don't know enough about your knee but could it possibly be a dislocated knee cap? Anyway, goggle it and see please. I think there are ways you can work with it. And there may be different types of compression you can put on your knee but what works for one person, may not work for another, Also, you might need an x-ray or/and MRI?

My legs used to hurt terrible during the day and then when I tried to rest it felt like someone had a rubber band and was pulling my legs and legs wood just twitch and twitch and I couldn't sleep that's when I started taking Lyrica and it really did the trick that was the end of the pain in my legs and the RLS at night I also started walking with a cane and that helped too, I switch hands as it is both legs
I am hoping they this helps you compression stockings did not help I do wear support pantyhose sometimes under my pants and that seems to help my legs
They usually start you on a low dose just see how you tolerate it then they have to raise it until it works so be patient if you try it you will gain a few pounds and instead of taking it once a day I take it three times a day so I get through the day and the night good luck to you! ❤, 🌞Nan