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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyFibroTeam Member asked a question 💭
Valley Cottage, NY

After failing with almost all meds out there for us fiber folks, my rheumatologist told me to follow up with a pain management group. The doctor there has me starting on .5mg of Naltrexone. I've only started it a few days ago and so far I see no changes, but I was told I would start on a low dose and build up. I was advised it could take 3 to 4 months before noticing any relief.

I was wondering if anyone else has tried this yet and what their success was, if any.

Thanks!
Dorothy

October 31, 2018
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Answer Summary

Members shared mixed but often hopeful experiences with Low Dose Naltrexone for fibromyalgia, with dosing strategies varying widely from 0.5mg... Read more

Members shared mixed but often hopeful experiences with Low Dose Naltrexone for fibromyalgia, with dosing strategies varying widely from 0.5mg to 10mg and results ranging from immediate relief to requiring several weeks or months to notice benefits. Several members described significant improvements including reduced pain, increased energy, lifted brain fog, fewer migraines, and better mood, though some experienced side effects like insomnia during the first week or digestive issues that led them to discontinue use. A recurring theme was the importance of patience and finding the right dosage, with many members encouraging others to work up gradually and stay hopeful, as LDN appears to help roughly 40% of people with autoimmune conditions and fibromyalgia.

A MyFibroTeam Member

Naltrexone was my savior! I started with 4.5 mg and I am now on 10 mg which is the highest you can go to keep it low dose. I became more energetic, my migraines went away. My pain subsided for a while. I was like a whole new person. I literally was no longer living in my bed. No side effects at all. I have been on it a little over a year. It started working about 2 weeks after taking it. I am just now starting to feel some Pain again, fibro fog, and a little fatigue.

November 7, 2018
A MyFibroTeam Member

I am a physician who specializes in treating Fibromyalgia. I start LDN a little higher and increase the dose every few weeks with 4-8mg usually working. I get very good results but I also take a number of other factors in to account when treating Fibromyalgia.

January 29, 2019
A MyFibroTeam Member

It worked immediately for me. It gave me energy and took away my migraines. It was a God send. Started on 4.6mg went up t0 10mg. Been off 2 months now about to start at 5th again.

March 25, 2019
A MyFibroTeam Member

Hello @A MyFibroTeam Member. My doctor told me the insomnia is only temporarily which for me was true. I had a hard time sleeping the first week but I didn't care. I didn't need it as my energy was through the roof. I got back down to my normal sleep schedule about a week later. Hope this helps. Hugs Amzel

April 1, 2019
A MyFibroTeam Member

Just started 4.5 mg. So far I have not notice any changes...

March 8, 2019

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