Not typically a reaction to the meds. But definitely get yourself checked out, it could be an inflammation of the kidneys, bladder,etc . Nothing to play with. Get a urine test and urine culture done to rule out infection

I'm on pregablin too, have you got swelling on your legs too. I have the same as you but gets better as the day goes on

Iv been referred to a urologist

Have you been to a kidney doctor?