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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyFibroTeam Member asked a question ๐Ÿ’ญ
Pelham, AL

I was recently diagnosed with very early Sjogrens Syndrome. I was put on Plaquenil for it. It is also used for Rheumatoid Arthritis. Is it just me or is the new medication also helping my Fibromyalgia. I began 6 milligram Naltrexone in March and had great results. Put these 2 together with my Cymbalta and I hardly ever nap or have flares.

Does anyone else take Plaquenil and think it helps their fibromyalgia.

April 26, 2017
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Answer Summary

Members shared experiences with Plaquenil for autoimmune conditions, with several reporting that it helped reduce their fibromyalgia symptoms... Read more

Members shared experiences with Plaquenil for autoimmune conditions, with several reporting that it helped reduce their fibromyalgia symptoms when combined with other medications like Naltrexone and Cymbalta, though some found it stopped working after a few years or chose to discontinue due to concerns about long-term effects. Many members emphasized the importance of regular liver enzyme monitoring when taking Naltrexone, with one sharing that their enzymes skyrocketed after just one month despite initially excellent pain relief. A recurring theme was the trial-and-error nature of managing overlapping autoimmune conditions and fibromyalgia, with members balancing medication benefits against side effects like sleep disruption, sweating, and withdrawal symptoms, while also incorporating alternative approaches such as water therapy, heat, CBD, and exercise.

A MyFibroTeam Member

I took Duluxetine/Cymbalta for 3 mos. initially it was a miracle drug. It took away all my fibrobsymptoms but I couldn't tolerate the side effects. Did not allow me to sleep more than 3-4 hrs max per day (didn't allow me to nap either), persistent yawning, profuse sweating w/ physical exertion, night terrors, & occasional blurred vision. Dr said side effects would eventually dissipate but started to feel weird from sleep deprivation. When I decided I no longer wanted to take it, medication dosage was gradually decreased over time. The most noticeable withdrawal symptom was vertigo!

Currently, I am in Water Phys Therapy (significantly reduces pain), Flexeral & medical marijuana occasionally, CBD oil or edibles, recommended exercises for water & land, swim, bike & hike. Winter (cold temperatures) is harsh on body& Fibromyalgia flares up a lot (body aches likes flu, pronounced fuzzy brain b/c of intense pain, & fatigue. Remain wrapped in electric blanket & heating pads.

April 28, 2017
A MyFibroTeam Member

I was actually on plaquenil 12 years ago when first diagnosed with Bechet's disease and then I was diagnosed with fibro secondary, I was also on colchicine & was on so much meds, I stopped everything myself & only take what's needed for the symptoms as they arise, however I am now thinking of speaking to my doc and maybe starting back on the plaquenil. Hope you continue to feel relief. ๐Ÿ˜Š

April 27, 2017
A MyFibroTeam Member

I am on .gabapentin and lexapro. I took the plaquenil for 3 years and didnt seem to help so we changed it. I also take tylenol extra strength in the morning and sometimes if needed in the afternoon. I also have tramadol but I dont take that on a regular basis unless i am having a flare

April 27, 2017
A MyFibroTeam Member

I was diagnosed with lupus , and also have fibro ,my Dr put me on plaquenil. It does help alot

January 8, 2020
A MyFibroTeam Member

https://en.wikipedia.org/wiki/Hydroxychloroquine it's a hard read, but my rheumatologist told me it does that.. seems to be pretty full on stuff..

May 29, 2017

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