Yes this is a normal side affect to the med. and it does take up to two weeks for the meds or side affects to go away....any meds you start taking it always takes up to two weeks for you body to adjust to them.
Pharmacy Tech

I've been on both for a few years the side effects do go away. This combination helped bring me out of a deep depression. Wishing you well.

Hi I was on celebrex but they took me off as said they were not using this drug anymore now on tramadol and pregablin but not much good

Yes indeed. Some side effects are to be expected. Never ever ever stop taking it! Let the doctor wean you off.

I take the two together as well, at first it made me tired and dizzy and a little off balance. I don't have those problems anymore, stick with it. If you find it's still giving you the same side effects after a couple weeks go to your doctor, he may cut back on the strength of the effexor. All new meds you should give a couple weeks to adjust. Good luck