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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyFibroTeam Member asked a question 💭
Ottawa, ON

Has anyone had better results with Effexor than Cymbalta. I will be tapering off Cymbalta to try something else, but I was not expecting the Dr. to suggest Effexor. He said only the SNRI category of antidepressant meds help Fibro.

March 8, 2016
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Answer Summary

Members shared mixed experiences comparing Effexor and Cymbalta for fibromyalgia, with many finding Cymbalta more effective for nerve pain and... Read more

Members shared mixed experiences comparing Effexor and Cymbalta for fibromyalgia, with many finding Cymbalta more effective for nerve pain and anxiety, while others appreciated Effexor for providing more energy despite increased sweating and weight gain. Several members emphasized the importance of never stopping either medication abruptly due to severe withdrawal symptoms including brain zaps, electrical impulses, irritability, and instability, with some noting they felt trapped on medications that had stopped working but were too difficult to discontinue. A recurring theme was the challenge of distinguishing whether daily exhaustion, pain, and mood changes stem from fibromyalgia itself or medication side effects, with most agreeing that these drugs only take the edge off rather than providing complete relief.

A MyFibroTeam Member

I've had better results with Cymbalta than Effexor. That being said, Cymbalta is highly addictive and very bad withdrawals are the norm.

April 6, 2016
A MyFibroTeam Member

I am very sensitive to medication. There was meds that had me gain 60 plus pounds. I have had no side effects with Cymbalta. I thought my body was adjusting to the meds so I went off them. Only then do we tealize how much the meds wete working. Just a thought.Soft hugs.

March 15, 2016 (edited)
A MyFibroTeam Member

I tapered off of Cymbalta and went to a higher dose of Effexor. It's OK but what else are we going to do when struggling with our problems.. The withdrawal wasn't fun but better with already being on Effexor.

March 9, 2016
A MyFibroTeam Member

Please do not suddenly stop taking any SSRI or SNRI. Serotonin syndrome/withdrawal can be life threatening.

March 9, 2016
A MyFibroTeam Member

Actually, Savella is approved for FMS. It is a SNRI and has helped alleviate my fibro pain more so than cymbalta. It isn't the first drug of choice because there is no generic form available. I pay $57 for 60 pills. And that's with insurance.

March 9, 2016 (edited)

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