Yes, there are many warnings about Tramadol and Cymbalta which is what I've been prescribed as well. I've heard that the serious side-effects are more common in certain populations, such as middle-aged individuals. It's definitely something to consider.

As for the effectiveness of Tramadol, I think it is one of the better prescription pain medications I've been prescribed. I don't get any of the "high" sort of feelings I get from things like Delaudid but it still takes the edge off of my mild symptoms. OTC painkillers are like sugar pills for me.

Hope this helps!

I am on Tramadol, 50mg. I take it 6 to 8 times a day when the pain is bad. I find it very helpful with few side effects. I take it with 500mg acetaminophen (only twice a day).

Not strong enough for me so I take precocet 10/325 even that does help anymore, my body adapts to medication very fast

I take Tramadol HCL & Acetaminophen only when nothing else helps when pain is persistent and getting out of control and it's a lifesavor! Makes me tired though 😃

Just started taking it was told take two times a day but not everyday..