Answer Summary

Members shared mixed experiences comparing pregabalin (Lyrica) and gabapentin (Neurontin) for fibromyalgia and chronic pain, with several... Read more

Members shared mixed experiences comparing pregabalin (Lyrica) and gabapentin (Neurontin) for fibromyalgia and chronic pain, with several noting that while pregabalin tends to have fewer side effects, gabapentin is more affordable and may be worth trying despite potential grogginess, brain fog, or leg swelling. Many members described significant weight gain on both medications, with gabapentin causing one member to gain four stone in a year and pregabalin being associated with greater weight gain overall, though pain relief varied widely from no help at all to noticeable improvement when taken consistently at higher doses. A recurring theme was the deeply personal nature of medication response, with members emphasizing the importance of working closely with doctors to find the right fit, adjusting doses gradually, and staying on a medication that works rather than switching if side effects are manageable.