Answer Summary

Members shared mixed experiences with Cymbalta and appetite, with some describing days of complete disinterest in food while others reported... Read more

Members shared mixed experiences with Cymbalta and appetite, with some describing days of complete disinterest in food while others reported fluctuating hunger or even significant weight gain despite reduced appetite. Several members noted that appetite changes were often temporary, with one person losing 15 pounds during a clinical trial and another experiencing initial appetite loss that returned within a few weeks, while others attributed their eating patterns more to pain and fatigue than the medication itself. A recurring theme was the importance of eating consistently to take other medications safely, even when hunger is absent, and being aware that Cymbalta can affect both appetite and weight in unpredictable ways.