Answer Summary

Members shared their experiences with duloxetine for fibromyalgia pain and depression, with many finding that 60 mg (sometimes split into... Read more

Members shared their experiences with duloxetine for fibromyalgia pain and depression, with many finding that 60 mg (sometimes split into morning and evening doses) provided meaningful relief, though some noted the benefits lessened over time or required additional medications like nortriptyline or pregabalin to manage symptoms fully. Several members emphasized that while the medication helped reduce pain intensity and flare-ups, it did not eliminate symptoms entirely, and common effects included decreased appetite and occasional drowsiness when combined with other treatments. A recurring theme was the critical importance of never stopping duloxetine abruptly, as multiple members described severe withdrawal symptoms and urged always working closely with a doctor to taper off safely if discontinuation becomes necessary.