I’ve been on 4.5mg for two months now. It is helping with the pain. I do have some bad days but not as many as I had before. However, I noticed I’ve become more depressed and I have been getting a lot of migraines. I can’t seem to get motivated to do much of anything anymore even though I have less pain. Going to take it every other day to see if my depression lifts any and if not I’m going to have to stop taking it. Hopefully I can find something else that will help.

I started taking 4.5mg on Thursday (four days ago). So far, I'm still pretty queasy, but that seems to be the only negative side effect, so far.

I started taking Naltrexone in Sept. 2019, it has I proved my pain enormously. I take 25 mg in the morning. Yah, I know way more than has been recommended, I am very medication resitent. Everyone is different. I also get nerve blocking shots in my back every two months. They are also very beneficial. I also take 3600 mg per day of gabapentin and 200 mg of trazadone and ingest Cannabis oil....plus alot of supplements and regular exercise. I feel often there is a big commination of drugs, etc. to help, not cure...fibro is FOREVER! Still am very fatigued for several days at a time when i over do it, which i often do....got to get stuff done!!!

Good question and one I was going to ask. There is so much talk right now about using it for FM but I haven’t heard how effective it is. Thanks for asking.