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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyFibroTeam Member asked a question 💭
Whangarei, NZ

I take a 5mg dose of Amitriptyline every night before bed to help me sleep and to control anxiety. My Doctor thinks I should increase the dose to 20 mg for it to be really effective. But I find that a small dose of 5 mg is doing the job and does to give me side effects to deal with. Does anyone else feel they need a much smaller dose than normal to get the benefits as my GP gives me an odd look when I say a small dose actually works for me.

October 24, 2017
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Answer Summary

Members validated the original poster's experience with low-dose Amitriptyline, with several sharing that they also found smaller doses... Read more

Members validated the original poster's experience with low-dose Amitriptyline, with several sharing that they also found smaller doses effective and that each person's body responds differently to medication. Many members described common side effects at higher doses, particularly dry mouth and next-day grogginess, with some switching to alternatives like Nortriptyline or Ativan when Amitriptyline became intolerable or less effective over time. A recurring theme was the importance of self-advocacy with doctors, trusting one's own body, and resisting pressure to increase dosage if a lower amount is working without unwanted side effects.

A MyFibroTeam Member

I took Amitriptyline and didn't like the constant dry mouth, no matter how much I drank
I was only on a low dose.
If the low dose works for you, stand up for yourself and tell your doctor you are not increasing the dose. If he/she will not respect your decision, time to find a gp who will. At the end of the day it is your body that is dealing with the side effects of the medication not your doctor.
You are strong warrior. You can do this. Hugs.💖

October 25, 2017
A MyFibroTeam Member

When they gave it to me back in the 1980's they started with 100mg! then went up to 150mg!!!! I was a zombie. They didn't have a dx for me, and thought it was stress, of course. I've since learned that the lower the dose for sleeping with fms, the better.
Good luck!
((((HUGS))))

October 29, 2017
A MyFibroTeam Member

I also take 5 mg and it works just fine. My dr also was surprised that this low dose worked but it is great. No need to increase I was told , each person is different.

October 27, 2017
A MyFibroTeam Member

I am super sensitive to drugs and can't cope with side effects so for me, it has to be a low dose or no dose. The higher the dose, the stronger the side effects which in themselves can be as hard to cope with as the symptoms you are trying to alleviate. Finding the right dose for you is not always what your GP thinks is right for you, but we know our own bodies and how much is likely to be too much.

October 24, 2017
A MyFibroTeam Member

I used to take 25mg dose of Amitryptalyne but couldn’t deal with the dry mouth and grogginess the next day so stopped taking them, I didn’t think of trying to cut down the dose...

October 24, 2017

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