With Lyrics I gained a lot of weight quick making it hard to breath, with Cymbalta it changed my attitude. I was very hateful. My mom and boyfriend at the time told me I should stop taking it. They did all that but didn't help with the pain or anything else.

ThankYou. ...I've noticed most have gained weight with Lyrica...makes me worry I can't afford to gain more weight....I've cut alot of salt and sugar down which I can see improvement and I've grown a vegetable garden. It's a long road ahead....thankyou again for your input.

Amitriptyline 30mg, but only comes in 10's or 25's, so I take 25. Has helped me quite a bit. Took ages to get used to them because they made me very drowsy at first. I got careless and missed taking them for a few days, also over did it physically, and I am paying for it now.
I can categorically say, yes amitriptyline helps me and I won't be going off them again in any hurry!
I have also found that the 2mg of melatonin every night has improved my sleep enormously.
Still having a bad week with pain but I know from experience that it will get a bit better soon.

I started off with lyrica and it just kept making me gain weight so did the cymbalta and they didn't help my pain I take amitriptyline 50mg at bedtime I can't tell that it does anything

I tried Lyrica & had bad side effects, so the doc weaned me from that onto Cymbalta which gave me the same bad side effects. Everyone reacts differently though, so it's trial & error for each individual unfortunately. Best of luck in finding what is best for you. Susan