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A MyFibroTeam Member asked a question 💭
Manchester, UK

Just wanted to know what medications people have found most effective? I can't have opiates as I have bad reactions so I'm currently on lyrical, amitriptaline, propranolol and a whole other range of stuff but I'm still really struggling to do the simplest of tasks such as going to the toilet... Need help and to know of any medication that might help.. Tia x

May 28, 2016
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Answer Summary

Members shared a wide range of medication experiences in response to someone struggling with severe pain and limited mobility despite being on... Read more

Members shared a wide range of medication experiences in response to someone struggling with severe pain and limited mobility despite being on Lyrica, amitriptyline, and propranolol. Several members found relief with gabapentin (noting it reduced pain significantly overnight), Cymbalta (often paired with Lyrica), and muscle relaxants like Skelaxin, while others described serious side effects including weight gain, swelling, digestive issues, and difficult withdrawal experiences that led them to taper off medications entirely. A recurring theme was the importance of open communication with doctors, trying non-medication approaches like eliminating trigger foods or water-based exercise, and offering emotional support during flare-ups when even the smallest tasks feel impossible.

A MyFibroTeam Member

I was on gabapentin for a couple of years but, the doctor kept upping the meds cos my body got used to them and I started getting pain again then he put me on cymbalta which was great at first then I gained two stone, diviculitis , stomach lesions and Gerd so now slowly tapered everything down to nothing. The withdrawal is horrendous even though i am doing it properly.

May 30, 2016
A MyFibroTeam Member

It sounds like you are on similar medications that I am. I find that gabapentin (GA ba PEN tin)
(Brand Names: Gralise, Horizant, Neurontin, Gabarone) reduces my pain levels from a 15 to a 9-10 overnight it seems. Lyrica made me gain quite a bit of weight (30+ lbs) and I was always really tired, depressed and moody. Plus my legs would swell significantly.
I also eliminated a lot of soy and wheat products from my diet. Those also tend to flare up my pain and my headaches.
Hoping this helps and praying for rest for you.

May 28, 2016
A MyFibroTeam Member

I have come off all my meds and at last I am starting to feel normal again

June 2, 2016
A MyFibroTeam Member

Bram I wish not an option I am afraid 😳

May 31, 2016
A MyFibroTeam Member

get rid of the drugs there killing you, try cannibis buger if its legal or not.

May 30, 2016

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