Answer Summary

Members widely confirmed that gabapentin contributed to weight gain, with several sharing they put on anywhere from a few pounds to 15 pounds... Read more

Members widely confirmed that gabapentin contributed to weight gain, with several sharing they put on anywhere from a few pounds to 15 pounds or more, and some experiencing frustrating water retention or swelling that made weight loss feel nearly impossible. Several members shared alternative medications and strategies, including switching to Gralise (an extended-release version taken once at night that helped one member lose the gained weight), noting that Lyrica caused even more weight gain or cognitive side effects, and mentioning Topamax as a potentially better option for weight management. A recurring theme was the difficult trade-off between finding a medication that effectively manages pain and dealing with unwanted side effects, leaving many members feeling stuck between relief and frustration.