HI There! I'm going to be totally honest with you. I was doing the handful of drugs for almost 8 years, until a wife of a VP from my former job place - who was 60 yrs. old at the time, former OR nurse - called me and asked me "What drugs are you taking, and how much do you know about these drugs?" All of these pain killers, muscle relaxers, and anti-depressants make conditions like ours much worse. In early 2011, I weaned myself off of all the drugs I was on, and started taking vitamins and supplements that my body was starving for. Prescription drugs not only interfere with our total endocrine system, and mess with our brain chemicals, but they also deplete us even more of nutrients and vitamins that we don't get enough of to begin with, with our horrible diets. It was not easy, but five years later I am doing so much better. I ache from time to time, and still struggle with fatigue with environmental changes, but I have more brain clarity, I'm not in bed-ridden pain, and I look healthier. Find yourself a good naturopathic doctor, see a good chiropractor/keinesiologist to work with you. These are the health care professionals that understand what the body needs to heal. It's either that, or your health will continue to go downhill, and get worse. I just cringe when I read through the posts on this site, and see all the drugs that everyone's taking. I was there once, and knowing what I know now, and what I've learned about diet and alternative medicine, I feel bad for those who are not educating themselves more about the dangers of prescription drugs. Drugs are just a termporary fix - they do not heal the body. I hope that this information helps you. A good book to read is called "Treating and Beating Fibromyalgia & Chronic Fatigue Syndrome" by Dr. Rodger Murphree. It's my night stand health bible. I refer to it quite often, as I continue to tweak my regimen.

Funny story. I hadn't noticed that I've been on Duloxetine for some time now. I've begun to ignore the drug names anymore. I do like it. It has made my symptoms manageable when I'm doing everything right and when the world is being right by me too. :). I do notice though that slowly it is less and less effective just like everything else. I'm still in a relatively manageable pain threshold with flares that are relatively manageable as well.

I'm taking this currently o n 90mg. Haven't noticed too Manny side effects besides dry. Mouth. I think it's helping.

I was diagnosed in sept 2015. started out on 30mg once a day for the first week then went to 60mg once a day. i was on this until the end of december 2015 and was then uped to 60mg 2x a day. worked great for awhile but now back to having constant leg pain so hopefully it will work better for you.

I take 60 mg of Cymbalta daily. I notice that it helps with my morning stiffness and the depression that sometimes goes with chronic pain. No side effects for me