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I Have Tried Lyrica, Cimbalta And Amytriptiline, But Had Adverse Reactions. Currently Using Tylenol. Any Other Pain Relief Options?

A MyFibroTeam Member asked a question 💭
Des Plaines, IL
January 7, 2016
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Answer Summary

Members responding to someone seeking pain relief alternatives after adverse reactions to Lyrica, Cymbalta, and Amitriptyline shared a wide... Read more

Members responding to someone seeking pain relief alternatives after adverse reactions to Lyrica, Cymbalta, and Amitriptyline shared a wide range of medications that have helped them, including Savella, Carbamazepine, Gabapentin, Effexor, Tramadol, and naproxen, though many emphasized that finding the right medication often involves trial and error due to individual side effects. Several members described non-medication approaches that provided relief, such as chiropractic care, acupuncture, regular exercise, heat therapy, heated blankets for nighttime stiffness, and eliminating trigger foods like gluten, dairy, shellfish, and wheat. A recurring theme was the importance of working closely with doctors to find personalized solutions, being patient through the process of adjusting dosages, and combining multiple approaches rather than relying on medication alone.

A MyFibroTeam Member

I am now on Gabapentin and it seems to be helping some. I am also on Effexor and while it is a depression medication it also has an element in it that fights pain signals. You probably should ask your doctor about what the next step is for you. I was taken off all narcotics because they were tearing my stomach up. Since then, I alternate Tylenol and Motrin. The Motrin seems to work better for me. Good luck.

January 7, 2016 (edited)
A MyFibroTeam Member

I took gabapentin (neurotin) for about 5 years, then switched to Lyrica for about a year. I am now off both due to the side effects. I find naproxen (aleve) helps. My biggest helper though has been eliminating trigger foods and limiting gluten and dairy. Hope that helps.

January 8, 2016 (edited)
A MyFibroTeam Member

I use Tramadol without any side effects. I am also on Cymbalta which does nothing for my pain.

January 8, 2016 (edited)
A MyFibroTeam Member

Sorry to hear that. Seeing a chiropractor, acupuncturist, and walking or exercising(releases endorphins-natural pain killer) helps. Heat and ice, I sleep with a heated blanket at night so I don't wake up so stiff. Ibuprofen, naproxen, gabapentin are some I tried. But the naproxen sent my heart rate through the roof, gabapentin and lyrica made me severely depressed. Cymbalta has worked. Have you tried a higher dose of cymbalta? Or others like it? I wish you luck! Be careful some of these drugs are awful :/ I hope you feel better!

January 7, 2016 (edited)
A MyFibroTeam Member

Same. I did just start using Gabapentin, it def helps the sleep at night issue. I'm not sure yet about the pain itself but I'm pretty sure once I find the right dosage, it will be a good med. Also, I have taken Tramacet for years for pain. Two in the morning and sometimes 1 in the afternoon.
My one doctor has just prescribed Effexor but I'm not sure I will even get the prescription filled cos it is supposed to have adverse reactions with the tramadol! (Tramacet is tramadol and tylenol together)
I hope you can find more than tylenol to get some pain relief!

January 7, 2016 (edited)

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