Hi, im Rob suzys partner. So a smooth muscle antibody test is to determine whether autoimmune responses in fibromyalgia antigens of the muscle tissue have relevance to the still pathogenesis of the syndrome. So basically as i understand it the test is to find out if there is an absence of auto antibodies in primary fibromyalgia.such as anti-n-methyl-d-aspartate. The test itself will be done by venepuncture usually by drawing blood from inside the elbow or back of the hand. Not to worry you but a high amount of smooth muscle antibodies probably means you could have type 1 form of autoimmune hepatitis. A lower amount may mean type 2 form of hepatitis or if no smooth muscle antibodies are found it could mean your liver symptoms are being caused by something different. In a nutshell the test is to determine the flow of blood through arteries and veins where they control the vessel and liver function. The test is also used to detect lupus so maybe a definitive way to determine whether its fibro or lupus. I hope my findings dont alarm you or upset you, im sure its just to rule out the latter, but these are the reasons that the test is done. Sending hugs and if any further information is required please do ask me and i shall put my brain box to work as best i possibly can to find any answers for you. Regards,
Rob

What does positive anti-smooth muscle antibody mean?
What Does a Positive Smooth Muscle Antibody Test Mean? Normally, very little to no ASMAs are found in your blood. If your blood test shows a high amount of ASMAs, you may have autoimmune hepatitis. It means that your immune system is attacking healthy cells in your liver using autoantibodies.Oct 18, 2021
Anti-smooth muscle antibody is a blood test that detects the presence of antibodies against smooth muscle. The antibody is useful in making a diagnosis of autoimmune hepatitis. Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand.

I also read that if the test is positive it means you have autoimmune hepatitis. I didn't read the whole thing so if you google it. It may help. Hope you get things straightened out.

I have never heard of this but maybe you could share if you get the answer hope it all works out

Oh sorry, I forgot to note that some researchers believe certain DNA viruses cause the body to express FM (this is environmental factors). Note the genetic susceptabilities that have been studied: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC63...