Flexoril might help with sleep issues. If you get that zombie feeling that @A MyFibroTeam Member was talking about you could see about utilizing that in the evening or just before bedtime. And figure something else out for during the day. I used to take it for muscle spasms and pain. I don't know much about methotrexate. Drugs.com is a great source for information. Their site is easily understood and navigated.

Mentioned Users

A MyFibro...

https://www.drugs.com/methotrexate.html

First night, no help with sleep.

I don't know about Methotrexate but I have had lots of experience with Flexeril and I did not like it at all! The reason that I say that is because I Flexeril would have me feeling and looking like a zombie many hours after I had taken it. I was prescribed a very low dosage and to take it at night, but I would still feel the effects of severe drowsiness well into the next day. I really hope that it works better for you though.